SCHEMBL8766711

SCHEMBL8766711

CCC(N)N(CCNCCN)C(N)CC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.50
CYP2C9 P11712 2/20 0.50
CA12 O43570 5/20 0.42
CA6 P23280 5/20 0.42
CA7 P43166 5/20 0.42
CA9 Q16790 5/20 0.42
CA14 Q9ULX7 5/20 0.42
CA5B Q9Y2D0 5/20 0.42
MEN1 O00255 2/20 0.42
RECQL P46063 2/20 0.42
KMT2A Q03164 2/20 0.42
CA2 P00918 4/20 0.40
CA4 P22748 4/20 0.40
CA5A P35218 4/20 0.40
TDP1 Q9NUW8 3/20 0.40
LMNA P02545 3/20 0.40
CA3 P07451 3/20 0.40
ALOX15 P16050 3/20 0.40
CA1 P00915 2/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7208214 0.78 CHRM2 (0.33) MEN1KMT2AALDH1A1TSHR
SCHEMBL10391766 0.78 CYP2C19 (0.48) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL18797279 0.78 CYP2C19 (0.48) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL2283392 0.77
SCHEMBL6754024 0.76 CYP2C19 (0.47) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL4124680 0.76 CYP2C19 (0.56) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL816413 0.76 CHRM2 (0.42) CA12CA6CA7CA9CA14
SCHEMBL6034866 0.75 CYP2C9 (0.45) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL5923765 0.74 CA12 (0.61) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL560601 0.74 CHRM2 (0.46) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300324-A Adding aminoethylethanolamine and-or polyalkylene polyamines THE DOW CHEMICAL COMPANY (US) 1994-04-05 US claimed
EP-0638063-B1 DECOLORIZATION OF POLYALKYLENE POLYAMINES DOW CHEMICAL CO (US) 1997-06-18 EP disclosed
EP-0498812-B1 A PROCESS FOR IMPROVING THE VISCOSITY AND FILTRATION RATE OF A WATER AND CLAY SLURRY DOW CHEMICAL CO (US) 1995-03-15 EP disclosed
EP-0638063-A1 DECOLORIZATION OF POLYALKYLENE POLYAMINES. DOW CHEMICAL CO (US) 1995-02-15 EP disclosed
US-5300324-A Adding aminoethylethanolamine and-or polyalkylene polyamines THE DOW CHEMICAL COMPANY (US) 1994-04-05 US disclosed
EP-0334950-B1 IMPROVED CASTING PROCESS DOW CHEMICAL CO (US) 1994-01-05 EP disclosed
WO-1993022274-A1 DECOLORIZATION OF POLYALKYLENE POLYAMINES THE DOW CHEMICAL COMPANY (US) 1993-11-11 WO disclosed
EP-0346073-B1 Manufacture of non-whiteware ceramic articles DOW CHEMICAL CO (US) 1993-10-20 EP disclosed
US-5227528-A Decolorization of polyalkylene polyamines THE DOW CHEMICAL COMPANY (US) 1993-07-13 US disclosed
US-5205971-A Casting slip containing dispersant, binders and acyclic polyamine additive for increased green strength THE DOW CHEMICAL COMPANY (US) 1993-04-27 US disclosed
US-5151130-A Slurry with a nonionic surfactant of amine polyoxyalkylene glycols THE DOW CHEMICAL COMPANY (US) 1992-09-29 US disclosed
US-5057467-A Polyalkylene polyamine and latex THE DOW CHEMICAL COMPANY (US) 1991-10-15 US disclosed
US-5034448-A Ceramic formed in a casting process with polyalkylene polyamine THE DOW CHEMICAL COMPANY (US) 1991-07-23 US disclosed
EP-0334950-A4 IMPROVED CASTING PROCESS 1991-05-22 EP disclosed
US-4915890-A Casting process THE DOW CHEMICAL COMPANY (US) 1990-04-10 US disclosed
WO-1989012035-A1 MANUFACTURE OF NON-WHITEWARE CERAMIC ARTICLES THE DOW CHEMICAL COMPANY (US) 1989-12-14 WO disclosed
EP-0346073-A1 Manufacture of non-whiteware ceramic articles THE DOW CHEMICAL COMPANY (US) 1989-12-13 EP disclosed
WO-1989002355-A1 IMPROVED CASTING PROCESS THE DOW CHEMICAL COMPANY (US) 1989-03-23 WO disclosed