Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ADH1B | P00325 | 2/20 | 0.44 |
| ▸ | ADH1C | P00326 | 2/20 | 0.44 |
| ▸ | ADH1A | P07327 | 2/20 | 0.44 |
| ▸ | ADH4 | P08319 | 2/20 | 0.44 |
| ▸ | ADH7 | P40394 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29038492 | 1.00 | TSHR (0.44) | TSHRADH1BADH1CADH1AADH4 | |
| SCHEMBL1696594 | 0.81 | — | — | |
| SCHEMBL8946852 | 0.78 | TSHR (0.44) | TSHRADH1BADH1CADH1AADH4 | |
| SCHEMBL10775738 | 0.78 | TSHR (0.50) | TSHRMAPTGPR84FDPSFFAR1 | |
| SCHEMBL10774678 | 0.78 | TSHR (0.50) | TSHRMAPTGPR84FDPSFFAR1 | |
| SCHEMBL10771326 | 0.78 | TSHR (0.50) | TSHRMAPTGPR84FDPSFFAR1 | |
| SCHEMBL9543091 | 0.78 | TSHR (0.50) | TSHRMAPTGPR84FDPSFFAR1 | |
| SCHEMBL10775700 | 0.78 | TSHR (0.50) | TSHRMAPTGPR84FDPSFFAR1 | |
| SCHEMBL10774657 | 0.78 | TSHR (0.50) | TSHRMAPTGPR84FDPSFFAR1 | |
| SCHEMBL10771376 | 0.78 | TSHR (0.50) | TSHRMAPTGPR84FDPSFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664811-B1 | GESTAGENICALLY ACTIVE 19,11-BRIDGED 4-ESTRENES | SCHERING AG (DE) | 1997-08-13 | — | — | EP | claimed |