SCHEMBL8766857

SCHEMBL8766857

CCCCCCCCc1c(O)ccc(C(=O)O)c1OC(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 4/20 0.47
PPARA Q07869 3/20 0.47
STAT3 P40763 2/20 0.44
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
PPARG P37231 2/20 0.41
BID P55957 3/20 0.41
MCL1 Q07820 3/20 0.41
BCL2L1 Q07817 2/20 0.41
BAK1 Q16611 2/20 0.41
EP300 Q09472 1/20 0.41
KAT2A Q92830 1/20 0.41
KAT2B Q92831 1/20 0.41
KAT5 Q92993 1/20 0.41
SAE1 Q9UBE0 1/20 0.41
PLK1 P53350 4/20 0.41
ALDH1A1 P00352 1/20 0.41
RARB P10826 1/20 0.41
PLK3 Q9H4B4 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8767070 1.00 KAT8 (0.47) KAT8PPARASTAT3ESR1ESR2
SCHEMBL8768058 1.00 KAT8 (0.47) KAT8PPARASTAT3ESR1ESR2
SCHEMBL8768056 0.95 ESR1 (0.44) KAT8PPARASTAT3ESR1ESR2
SCHEMBL8768033 0.90 ESR1 (0.46) ESR1ESR2MCL1ALDH1A1
SCHEMBL8767107 0.84 ESR1 (0.48) ESR1ESR2ALDH1A1
SCHEMBL28410733 0.80 PTPN11 (0.51) ALDH1A1
SCHEMBL15228082 0.79 PTPN11 (0.44) PLK1ALDH1A1
SCHEMBL8767056 0.78 ESR1 (0.47) ESR1ESR2ALDH1A1
SCHEMBL8766843 0.77 ESR1 (0.51) ESR1ESR2ALDH1A1
SCHEMBL27818384 0.77 KAT8 (0.51) KAT8PPARASTAT3PPARGBID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0585127-B1 Thermal Recording sheet JUJO PAPER CO LTD (JP) 1997-12-29 EP disclosed
EP-0570186-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1997-08-13 EP disclosed
US-5405821-A Containing a 4-hydroxyphenylarylsulfone color developer NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1995-04-11 US disclosed
EP-0570186-A1 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-11-18 EP disclosed