Methyl Alcohol

Methyl Alcohol

SCHEMBL8766880

CO.c1ccc2cc(C3CO3)ccc2c1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 12/20 0.49
SLC6A2 P23975 8/20 0.49
SLC6A3 Q01959 8/20 0.49
TSHR P16473 1/20 0.48
CYP2D6 P10635 6/20 0.45
KCNH2 Q12809 3/20 0.45
CYP3A4 P08684 2/20 0.45
HTR2C P28335 1/20 0.45
HTR2B P41595 1/20 0.45
KDM4E B2RXH2 1/20 0.44
DRD2 P14416 1/20 0.44
PARP1 P09874 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5852687 0.94 TSHR (0.54) SLC6A4SLC6A2SLC6A3TSHRCYP2D6
SCHEMBL29434698 0.94 TSHR (0.54) SLC6A4SLC6A2SLC6A3TSHRCYP2D6
SCHEMBL1119954 0.94 TSHR (0.54) SLC6A4SLC6A2SLC6A3TSHRCYP2D6
SCHEMBL10300821 0.94 TSHR (0.54) SLC6A4SLC6A2SLC6A3TSHRCYP2D6
SCHEMBL25543096 0.88 TSHR (0.52) SLC6A4SLC6A2SLC6A3TSHRCYP2D6
SCHEMBL15274534 0.86 SLC6A4 (0.44) SLC6A4SLC6A2SLC6A3TSHRCYP2D6
SCHEMBL9912114 0.82 SLC6A4 (0.48) SLC6A4SLC6A2SLC6A3TSHRCYP2D6
SCHEMBL8754871 0.78 SLC6A4 (0.50) SLC6A4SLC6A2SLC6A3CYP2D6KCNH2
SCHEMBL8828030 0.78 CYP2A6 (0.52) SLC6A4SLC6A2SLC6A3TSHRCYP2D6
Methyl Alcohol SCHEMBL10694365 0.76 SLC6A4 (0.58) SLC6A4SLC6A2SLC6A3CYP2D6KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0454463-B1 Process for producing epoxyalcohols of high optical purity ARCO CHEM TECH (US) 1997-08-13 EP disclosed
EP-0422897-B1 Recovery of water-insoluble epoxy alcohols ARCO CHEM TECH (US) 1994-06-22 EP disclosed
US-5278070-A Process for producing epoxyalcohols of high optical purity ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1994-01-11 US disclosed
EP-0454463-A2 Process for producing epoxyalcohols of high optical purity ARCO Chemical Technology, L.P. (US) 1991-10-30 EP disclosed
EP-0422897-A2 Recovery of water-insoluble epoxy alcohols ARCO Chemical Technology, L.P. (US) 1991-04-17 EP disclosed
US-4935101-A Process for the recovery of a water-insoluble epoxy alcohol ARCO CHEMICAL TECHNOLOGY, INC. (US) 1990-06-19 US disclosed