Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 11/20 | 0.37 |
| ▸ | PDE4A | P27815 | 8/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 4/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767582 | 0.92 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4DPDE2A | |
| SCHEMBL8767575 | 0.92 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4DPDE2A | |
| SCHEMBL8767570 | 0.92 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4DPDE2A | |
| SCHEMBL8767300 | 0.90 | PDE4B (0.40) | PDE4BPDE4APDE4CPDE4DPDE2A | |
| SCHEMBL8767053 | 0.89 | PTGDR (0.34) | PDE4BPDE4APDE4CPDE4DPDE2A | |
| SCHEMBL8767051 | 0.89 | PTGDR (0.34) | PDE4BPDE4APDE4CPDE4DPDE2A | |
| SCHEMBL13442832 | 0.89 | ESR2 (0.38) | PDE4BPDE4APDE4CPDE4DPDE2A | |
| SCHEMBL9062430 | 0.89 | ESR2 (0.38) | PDE4BPDE4APDE4CPDE4DPDE2A | |
| SCHEMBL13345615 | 0.89 | PDE2A (0.35) | PDE4BPDE4APDE4CPDE4DPDE2A | |
| SCHEMBL13480377 | 0.89 | ESR2 (0.38) | PDE4BPDE4APDE4CPDE4DPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |