SCHEMBL8767159

SCHEMBL8767159

CCS(=O)(=O)SS(C)(=O)=O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.33
KDM4E B2RXH2 1/20 0.31
CYP3A4 P08684 1/20 0.31
SLC6A4 P31645 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4104000 0.82
SCHEMBL7378142 0.73
SCHEMBL2223426 0.65
SCHEMBL14899275 0.64
SCHEMBL3194664 0.62
SCHEMBL10042105 0.62
SCHEMBL13391369 0.62
SCHEMBL9715494 0.62
SCHEMBL10629 0.60
Dimethyl Sulfone SCHEMBL27647353 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0680466-B1 PROCESS FOR PREPARING ISOCYANATES MONSANTO CO (US) 1997-08-27 EP disclosed
EP-0680466-A1 PROCESS FOR PREPARING ISOCYANATES. MONSANTO CO (US) 1995-11-08 EP disclosed
CN-1099384-A Process for preparing isocyanates MONSANTO CO (US) 1995-03-01 CN disclosed
US-5349081-A Dehydration, primary amine and carbon dioxide MONSANTO COMPANY (US) 1994-09-20 US disclosed
WO-1994017032-A1 PROCESS FOR PREPARING ISOCYANATES MONSANTO COMPANY (US) 1994-08-04 WO disclosed