Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767014 | 1.00 | GRM2 (0.39) | GRM2SIGMAR1CYSLTR2CYSLTR1CYP3A4 | |
| SCHEMBL8766039 | 1.00 | GRM2 (0.39) | GRM2SIGMAR1CYSLTR2CYSLTR1CYP3A4 | |
| SCHEMBL8766320 | 0.99 | GRM2 (0.37) | GRM2SIGMAR1CYSLTR2CYSLTR1CHRM2 | |
| SCHEMBL8766881 | 0.94 | CYP1A2 (0.38) | GRM2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8766611 | 0.88 | HDAC4 (0.36) | — | |
| SCHEMBL8765885 | 0.84 | CHRM1 (0.38) | GRM2SIGMAR1CYSLTR2CYSLTR1CHRM2 | |
| SCHEMBL8766470 | 0.84 | CHRM1 (0.38) | GRM2SIGMAR1CYSLTR2CYSLTR1CHRM2 | |
| SCHEMBL8766915 | 0.84 | CHRM1 (0.38) | GRM2SIGMAR1CYSLTR2CYSLTR1CHRM2 | |
| SCHEMBL8766485 | 0.83 | KDM4E (0.38) | GAAMAPT | |
| SCHEMBL8767261 | 0.83 | HDAC4 (0.38) | GRM2SIGMAR1CYSLTR2CYSLTR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601813-B1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5382688-A | Diamino compounds and their production method | CHISSO CORPORATION (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0601813-A1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1994-06-15 | — | — | EP | disclosed |