Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511077 | 1.00 | RARB (0.53) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9511182 | 1.00 | RARB (0.53) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9508589 | 1.00 | RARB (0.53) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9507501 | 1.00 | RARB (0.53) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9510984 | 1.00 | RARB (0.53) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9507524 | 1.00 | RARB (0.53) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9509751 | 1.00 | RARB (0.53) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9511119 | 1.00 | RARB (0.53) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9507350 | 1.00 | RARB (0.53) | RARBRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9510990 | 1.00 | RARB (0.53) | RARBRAB9AKDM4ENPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5702638-A | FERROELECTRIC LIQUID CRYSTALS MIXTURES HAVING HIGH NEGATIVE VALUES FOR THE DIELECTRIC ANISOTROPY | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |
| EP-0743971-B1 | PHENANTHRIDINE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | HOECHST AG (DE) | 1997-09-03 | — | — | EP | disclosed |
| EP-0743971-A1 | PHENANTHRIDINE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | HOECHST AG (DE) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021227-A1 | PHENANTHRIDINE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-10 | — | — | WO | disclosed |
| US-5348684-A | Organosilylalkyl or organosilylalkenyl compounds, process for preparing them and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-20 | — | — | US | disclosed |
| EP-0355008-B1 | Organosilylalkyl or -alkenyl compounds, process for their preparation and their use in liquid-crystal mixtures | HOECHST AG (DE) | 1994-04-13 | — | — | EP | disclosed |
| EP-0307880-B1 | Ferroelectric liquid-crystal mixtures | HOECHST AG (DE) | 1994-01-12 | — | — | EP | disclosed |
| EP-0268198-B1 | FERROELECTRIC LIQUID CRYSTALS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-09-01 | — | — | EP | disclosed |
| US-5013476-A | Ferroelectric properties, electro-optical indicating device | HOFFMANN-LA ROCHE INC. (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0355008-A2 | Organosilylalkyl or -alkenyl compounds, process for their preparation and their use in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-21 | — | — | EP | disclosed |
| EP-0268198-A2 | Ferroelectric liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1988-05-25 | — | — | EP | disclosed |