Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 5/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767553 | 1.00 | S1PR1 (0.34) | S1PR1EPHX2P2RX7PDE2AFFAR4 | |
| SCHEMBL8767562 | 1.00 | S1PR1 (0.34) | S1PR1EPHX2P2RX7PDE2AFFAR4 | |
| SCHEMBL8768349 | 0.89 | EPHX2 (0.39) | S1PR1EPHX2P2RX7PDE2AFFAR4 | |
| SCHEMBL20967289 | 0.88 | S1PR1 (0.39) | S1PR1EPHX2P2RX7PDE2AFFAR4 | |
| SCHEMBL16546428 | 0.87 | FFAR4 (0.32) | S1PR1PDE2AFFAR4 | |
| SCHEMBL16546530 | 0.85 | FFAR4 (0.32) | PDE2AFFAR4 | |
| SCHEMBL8768469 | 0.82 | USP5 (0.34) | HCRTR2 | |
| SCHEMBL8768455 | 0.82 | USP5 (0.34) | HCRTR2 | |
| SCHEMBL8768465 | 0.82 | USP5 (0.34) | HCRTR2 | |
| SCHEMBL7851837 | 0.82 | CYP2C9 (0.34) | EPHX2P2RX7PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |