Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4587412 | 0.67 | — | — | |
| SCHEMBL4587009 | 0.63 | — | — | |
| SCHEMBL27499532 | 0.62 | — | — | |
| SCHEMBL7607725 | 0.61 | — | — | |
| SCHEMBL655242 | 0.61 | TSHR (0.30) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL4586355 | 0.61 | — | — | |
| SCHEMBL655240 | 0.61 | TSHR (0.30) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL6284138 | 0.58 | — | — | |
| SCHEMBL6462072 | 0.58 | — | — | |
| SCHEMBL27656962 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630364-B1 | HYDROXY DERIVATIVES OF CYCLOHEXADIENE | ZENECA LTD (GB) | 1997-08-27 | — | — | EP | disclosed |
| US-5508444-A | Cyclic compounds | ZENECA LIMITED (GB) | 1996-04-16 | — | — | US | disclosed |
| EP-0630364-A1 | HYDROXY DERIVATIVES OF CYCLOHEXADIENE. | ZENECA LTD (GB) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993017994-A1 | HYDROXY DERIVATIVES OF CYCLOHEXADIENE | ZENECA LIMITED (GB) | 1993-09-16 | — | — | WO | disclosed |