Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767623 | 0.96 | PDE2A (0.38) | PDE2AEPHX2ESR2HPGDS1PR1 | |
| SCHEMBL8767621 | 0.96 | PDE2A (0.38) | PDE2AEPHX2ESR2HPGDS1PR1 | |
| SCHEMBL8767773 | 0.91 | EPHX2 (0.36) | PDE2AEPHX2ESR2HPGDS1PR1 | |
| SCHEMBL8767778 | 0.91 | EPHX2 (0.36) | PDE2AEPHX2ESR2HPGDS1PR1 | |
| SCHEMBL8768349 | 0.91 | EPHX2 (0.39) | PDE2AEPHX2S1PR1HCRTR1HCRTR2 | |
| SCHEMBL8767044 | 0.90 | EPHX2 (0.35) | PDE2AEPHX2ESR2HPGDS1PR1 | |
| SCHEMBL8767039 | 0.90 | EPHX2 (0.35) | PDE2AEPHX2ESR2HPGDS1PR1 | |
| SCHEMBL20967289 | 0.89 | S1PR1 (0.39) | PDE2AEPHX2S1PR1HCRTR1HCRTR2 | |
| SCHEMBL8771358 | 0.89 | CYP2C9 (0.41) | PDE2AEPHX2HCRTR1HCRTR2 | |
| SCHEMBL3437359 | 0.89 | CYP2C9 (0.41) | PDE2AEPHX2HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |