Methyl Alcohol

Methyl Alcohol

SCHEMBL8767938

CO.c1ccc(C2OC2c2ccccc2)cc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 5/20 0.46
PLAU P00749 1/20 0.44
TSHR P16473 2/20 0.44
CHRM2 P08172 3/20 0.42
CHRM4 P08173 3/20 0.42
CHRM5 P08912 3/20 0.42
CHRM1 P11229 3/20 0.42
CHRM3 P20309 3/20 0.42
SLC6A2 P23975 1/20 0.39
ADRA1A P35348 1/20 0.39
HTR2B P41595 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HTR1A P08908 1/20 0.38
CYP2C19 P33261 1/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3644410 0.91 EPHX1 (0.52) EPHX1PLAUTSHRCHRM2CHRM4
SCHEMBL63809 0.91 EPHX1 (0.52) EPHX1PLAUTSHRCHRM2CHRM4
SCHEMBL1199563 0.91 EPHX1 (0.52) EPHX1PLAUTSHRCHRM2CHRM4
SCHEMBL1103798 0.91 EPHX1 (0.52) EPHX1PLAUTSHRCHRM2CHRM4
SCHEMBL12914371 0.91 EPHX1 (0.52) EPHX1PLAUTSHRCHRM2CHRM4
SCHEMBL270441 0.91 EPHX1 (0.52) EPHX1PLAUTSHRCHRM2CHRM4
SCHEMBL1199046 0.91 EPHX1 (0.52) EPHX1PLAUTSHRCHRM2CHRM4
SCHEMBL6570141 0.88 EPHX1 (0.50) EPHX1PLAUTSHRCHRM2CHRM4
Lithium SCHEMBL29397282 0.88 EPHX1 (0.50) EPHX1PLAUTSHRCHRM2CHRM4
SCHEMBL4279301 0.88 EPHX1 (0.50) EPHX1PLAUTSHRCHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0454463-B1 Process for producing epoxyalcohols of high optical purity ARCO CHEM TECH (US) 1997-08-13 EP disclosed
EP-0422897-B1 Recovery of water-insoluble epoxy alcohols ARCO CHEM TECH (US) 1994-06-22 EP disclosed
US-5278070-A Process for producing epoxyalcohols of high optical purity ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1994-01-11 US disclosed
EP-0454463-A2 Process for producing epoxyalcohols of high optical purity ARCO Chemical Technology, L.P. (US) 1991-10-30 EP disclosed
US-4935101-A Process for the recovery of a water-insoluble epoxy alcohol ARCO CHEMICAL TECHNOLOGY, INC. (US) 1990-06-19 US disclosed