Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768251 | 1.00 | TSHR (0.48) | TSHRSLC6A2SLC6A3ADRA1AHTR2B | |
| SCHEMBL26966000 | 1.00 | TSHR (0.48) | TSHRSLC6A2SLC6A3ADRA1AHTR2B | |
| SCHEMBL1396587 | 1.00 | TSHR (0.48) | TSHRSLC6A2SLC6A3ADRA1AHTR2B | |
| SCHEMBL8768256 | 1.00 | TSHR (0.48) | TSHRSLC6A2SLC6A3ADRA1AHTR2B | |
| SCHEMBL18387696 | 1.00 | TSHR (0.48) | TSHRSLC6A2SLC6A3ADRA1AHTR2B | |
| Water SCHEMBL28267798 | 0.98 | TSHR (0.47) | TSHRSLC6A2SLC6A3ADRA1AHTR2B | |
| SCHEMBL28279521 | 0.84 | TSHR (0.35) | TSHRSLC6A2SLC6A3ADRA1AHTR2B | |
| SCHEMBL19090156 | 0.81 | BACE1 (0.38) | SLC6A2SLC6A3HTR2BSLC6A4 | |
| SCHEMBL14731081 | 0.81 | SLC6A2 (0.40) | TSHRSLC6A2SLC6A3HTR2BCYP2C19 | |
| SCHEMBL28253071 | 0.81 | SLC6A4 (0.31) | SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161476-A1 | COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF SWEAT MALODOR | Firmenich SA (CH) | 2023-04-12 | — | — | EP | claimed |
| WO-2022084548-A1 | COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF SWEAT MALODOR | FIRMENICH SA (CH) | 2022-04-28 | — | — | WO | claimed |
| EP-0581052-B1 | Use of tetrahydro-4-methyl-2-phenyl-2h-pyran as perfuming ingredient | FIRMENICH & CIE (CH) | 1997-09-03 | — | — | EP | claimed |
| EP-0581052-A1 | Use of tetrahydro-4-methyl-2-phenyl-2h-pyran as perfuming ingredient | FIRMENICH SA (CH) | 1994-02-02 | — | — | EP | claimed |
| US-5219836-A | Green, rose oxide odor | FIRMENICH SA (CH) | 1993-06-15 | — | — | US | claimed |
| US-20230404887-A1 | COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF SWEAT MALODOR | FIRMENICH SA (CH) | 2023-12-21 | — | — | US | disclosed |
| EP-4161476-A1 | COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF SWEAT MALODOR | Firmenich SA (CH) | 2023-04-12 | — | — | EP | disclosed |
| WO-2022084548-A1 | COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF SWEAT MALODOR | FIRMENICH SA (CH) | 2022-04-28 | — | — | WO | disclosed |
| US-5219836-A | Green, rose oxide odor | FIRMENICH SA (CH) | 1993-06-15 | — | — | US | disclosed |