Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768382 | 1.00 | ESR2 (0.41) | ESR2SIGMAR1OPRL1USP30TDP1 | |
| SCHEMBL8768354 | 0.98 | ESR2 (0.42) | ESR2SIGMAR1OPRL1USP30TDP1 | |
| SCHEMBL8768361 | 0.98 | ESR2 (0.42) | ESR2SIGMAR1OPRL1USP30TDP1 | |
| SCHEMBL8767507 | 0.94 | ESR2 (0.39) | ESR2SIGMAR1OPRL1USP30TDP1 | |
| SCHEMBL8767491 | 0.92 | ESR2 (0.44) | ESR2OPRL1USP30ESR1CYP3A4 | |
| SCHEMBL8767483 | 0.92 | ESR2 (0.44) | ESR2OPRL1USP30ESR1CYP3A4 | |
| SCHEMBL8768024 | 0.91 | ESR2 (0.39) | ESR2OPRL1USP30TDP1ESR1 | |
| SCHEMBL18895834 | 0.90 | OPRL1 (0.43) | ESR2OPRL1USP30ESR1CYP3A4 | |
| SCHEMBL9348236 | 0.89 | ESR2 (0.47) | ESR2OPRL1USP30ESR1CYP3A4 | |
| SCHEMBL9348230 | 0.89 | ESR2 (0.47) | ESR2OPRL1USP30ESR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789067-A1 | Cyclopentyl derivatives useful as liquid crystals | Rolic AG (CH) | 1997-08-13 | — | — | EP | disclosed |