Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374696 | 0.98 | FOLH1 (0.61) | FOLH1ALDH1A1ALOX15HPGDGAA | |
| SCHEMBL6043201 | 0.95 | FOLH1 (0.59) | FOLH1ALDH1A1ALOX15HPGDGAA | |
| Succinic Acid SCHEMBL6229447 | 0.90 | FOLH1 (0.53) | FOLH1ALDH1A1ALOX15HPGDGAA | |
| Terephthalic Acid SCHEMBL27748404 | 0.90 | TSHR (0.68) | FOLH1ALDH1A1ALOX15HPGDGAA | |
| Toluene SCHEMBL27935612 | 0.88 | FOLH1 (0.52) | FOLH1ALDH1A1ALOX15HPGDGAA | |
| SCHEMBL821015 | 0.86 | FOLH1 (0.50) | FOLH1ALDH1A1ALOX15HPGDGAA | |
| 4-Methylbenzoic Acid SCHEMBL7897437 | 0.82 | TSHR (0.58) | FOLH1ALDH1A1ALOX15HPGDGAA | |
| SCHEMBL70392 | 0.81 | FOLH1 (0.76) | FOLH1ALDH1A1ALOX15HPGDGAA | |
| SCHEMBL9668760 | 0.81 | GAA (0.55) | FOLH1ALDH1A1ALOX15HPGDGAA | |
| SCHEMBL30365583 | 0.81 | FOLH1 (0.76) | FOLH1ALDH1A1ALOX15HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945500-B | Mixing agonist based on GIP is for treating metabolic disorder and obesity | 印第安纳大学研究及科技有限公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-102123723-B | Glucagon/GLP-1 receptor co-agonists | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORP. (US) | 2016-05-25 | — | — | CN | disclosed |
| CN-104945500-A | GIP-based mixed agonists for treatment of metabolic disorders and obesity | UNIV INDIANA RES & TECH CORP | 2015-09-30 | — | — | CN | disclosed |
| CN-102105159-B | GIP-based mixed agonists for the treatment of metabolic disorders and obesity | UNIV INDIANA RES & TECH CORP | 2015-07-08 | — | — | CN | disclosed |
| CN-103641907-A | Glucagon/glp-1 receptor co-agonists | UNIV INDIANA RES & TECH CORP | 2014-03-19 | — | — | CN | disclosed |
| CN-102123723-A | Glucagon/GLP-1 receptor co-agonists | UNIV INDIANA RES & TECH CORP | 2011-07-13 | — | — | CN | disclosed |
| CN-102105159-A | GIP-based mixed agonists for the treatment of metabolic disorders and obesity | UNIV INDIANA RES & TECH CORP | 2011-06-22 | — | — | CN | disclosed |
| CN-1112180-C | Pharmaceutical composition containing drug/beta-cyclodextrin complex in combination with acid-base couple | SMIHKLINE BEECHAM PLC (GB) | 2003-06-25 | — | — | CN | disclosed |
| EP-0547825-B1 | Process for producing alpha-ketoamide derivative | SHIONOGI & CO (JP) | 1997-09-03 | — | — | EP | disclosed |
| CN-1133006-A | Pharmaceutical composition containing drug/beta-cyclodextrin complex in combination with acid-base couple | SMITHKLINE BEECHAM PLC (GB) | 1996-10-09 | — | — | CN | disclosed |
| US-5414122-A | Process for producing alpha-ketoamide derivative | SHIONOGI & CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| US-5258551-A | Amidation of benzoyl halide derivative with organic isocyanide; fungicide intermediates | SHIONOGI & CO., LTD. (JP) | 1993-11-02 | — | — | US | disclosed |
| EP-0547825-A2 | Process for producing alpha-ketoamide derivative | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-06-23 | — | — | EP | disclosed |