Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768899 | 0.91 | PPARA (0.57) | PPARAPPARGPPARDSOAT1HDAC6 | |
| SCHEMBL8769015 | 0.89 | PPARA (0.49) | PPARAPPARGPPARDSOAT1HDAC6 | |
| SCHEMBL8767691 | 0.88 | PPARA (0.50) | PPARAPPARGPPARDSOAT1HDAC6 | |
| SCHEMBL8767964 | 0.88 | SOAT1 (0.47) | PPARAPPARGPPARDSOAT1HDAC6 | |
| SCHEMBL8767877 | 0.87 | HDAC6 (0.59) | PPARAPPARGPPARDSOAT1HDAC6 | |
| SCHEMBL8767840 | 0.87 | PPARA (0.47) | PPARAPPARGPPARDSOAT1HDAC6 | |
| SCHEMBL8768932 | 0.87 | HDAC6 (0.50) | PPARAPPARGPPARDSOAT1HDAC6 | |
| SCHEMBL8768126 | 0.86 | PPARA (0.46) | PPARAPPARGPPARDSOAT1HDAC6 | |
| SCHEMBL8768853 | 0.85 | HDAC6 (0.49) | PPARAPPARGPPARDSOAT1HDAC6 | |
| SCHEMBL8768879 | 0.85 | PPARA (0.49) | PPARAPPARGPPARDSOAT1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639178-B1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | WELLCOME FOUND (GB) | 1997-09-03 | — | — | EP | disclosed |
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |