⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2045468 | 0.62 | — | — | |
| SCHEMBL2046811 | 0.60 | — | — | |
| SCHEMBL2045471 | 0.60 | — | — | |
| SCHEMBL2041033 | 0.57 | — | — | |
| SCHEMBL7857384 | 0.49 | MEN1 (0.75) | — | |
| SCHEMBL9747115 | 0.49 | — | — | |
| SCHEMBL651428 | 0.49 | MEN1 (0.75) | — | |
| SCHEMBL1194020 | 0.48 | TSHR (0.45) | — | |
| SCHEMBL1476442 | 0.46 | MEN1 (0.67) | — | |
| SCHEMBL219467 | 0.46 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632460-B1 | THIOPHENE DERIVATIVES FOR USE IN THE TREATMENT OF TUBERCULOSIS | UNIV VIRGINIA PATENT FOUNDATION (US) | 2018-02-28 | — | — | EP | disclosed |
| US-9333193-B2 | Compositions and methods for treating tuberculosis | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2016-05-10 | — | — | US | disclosed |
| US-8772502-B2 | Alkylsulfinyl-substituted thiazolide compounds | ROMARK LABORATORIES, L.C. (US) | 2014-07-08 | — | — | US | disclosed |
| US-20130317070-A1 | COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS | University of Virginia Patent Foundation d/b/a University of Virginia Licensing & Ventures Group (US) | 2013-11-28 | — | — | US | disclosed |
| EP-2635124-A1 | ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | Romark Laboratories, L.C. (US) | 2013-09-11 | — | — | EP | disclosed |
| EP-2632460-A2 | COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS | University Of Virginia Patent Foundation (US) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012061190-A1 | ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES L.C. (US) | 2012-05-10 | — | — | WO | disclosed |
| US-20120108591-A1 | ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES, L.C. | 2012-05-03 | — | — | US | disclosed |
| WO-2012040170-A2 | COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2012-03-29 | — | — | WO | disclosed |