SCHEMBL8768981

SCHEMBL8768981

C[Si](C)(C)Br.C[Si](C)(C)OC(=O)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL423208 0.93
SCHEMBL28601036 0.90
SCHEMBL4265048 0.82
SCHEMBL4758776 0.77
SCHEMBL1050079 0.77
SCHEMBL10925531 0.77
SCHEMBL28156524 0.77
SCHEMBL31477856 0.75
SCHEMBL31300447 0.75
SCHEMBL19582475 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639199-B1 PREPARATION OF 2-(PYRIDYL)ETHYL SUBSTITUTED PHOSPHORUS COMPOUNDS DU PONT (US) 1997-08-27 EP claimed
EP-0639199-A1 PREPARATION OF 2-(PYRIDYL)ETHYL SUBSTITUTED PHOSPHORUS COMPOUNDS. DU PONT (US) 1995-02-22 EP claimed
EP-0639199-A4 PREPARATION OF 2-(PYRIDYL)ETHYL SUBSTITUTED PHOSPHORUS COMPOUNDS. DU PONT (US) 1993-09-17 EP claimed
US-5194616-A Reacting vinylpyridine with a di- or tri-hydrocarbylphosphite in the presence of a silane, protic acid or lewis acid E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-16 US claimed
WO-1992012985-A1 PREPARATION OF 2-(PYRIDYL)ETHYL SUBSTITUTED PHOSPHORUS COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-08-06 WO claimed