Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.76 |
| ▸ | ANPEP | P15144 | 2/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | LAP3 | P28838 | 3/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Phenylalaninol SCHEMBL2521 | 1.00 | EPHX1 (0.76) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| L-Phenylalaninol SCHEMBL7422483 | 1.00 | EPHX1 (0.76) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| L-Phenylalaninol SCHEMBL177073 | 1.00 | EPHX1 (0.76) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| L-Phenylalaninol SCHEMBL81769 | 1.00 | EPHX1 (0.76) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| L-Phenylalaninol SCHEMBL31229492 | 0.98 | EPHX1 (0.73) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| L-Phenylalaninol SCHEMBL15467495 | 0.98 | EPHX1 (0.73) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| L-Phenylalaninol SCHEMBL7252746 | 0.98 | EPHX1 (0.73) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| L-Phenylalaninol SCHEMBL30996912 | 0.98 | EPHX1 (0.73) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| L-Phenylalaninol SCHEMBL27430394 | 0.98 | EPHX1 (0.73) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| L-Phenylalaninol SCHEMBL27521331 | 0.98 | EPHX1 (0.73) | EPHX1ANPEPSLC6A2TAAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129385-B2 | Substituted 5-hydroxy-3,4,6,9,9a, 10-hexanhydro-2h-1-oxa04a,8a-diaza-anthracene-6,10-dioness | SHIONOGI & CO., LTD. (JP) | 2012-03-06 | — | — | US | disclosed |