Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576592 | 0.85 | MEN1 (0.38) | MEN1KMT2AKDM4CGRM5L3MBTL1 | |
| SCHEMBL10308257 | 0.83 | MEN1 (0.33) | MEN1KMT2AKDM4CGRM5L3MBTL1 | |
| SCHEMBL6041516 | 0.82 | MEN1 (0.36) | MEN1KMT2AKDM4CL3MBTL1 | |
| SCHEMBL79105 | 0.82 | MEN1 (0.36) | MEN1KMT2AKDM4CL3MBTL1 | |
| SCHEMBL10578693 | 0.81 | CHRM2 (0.34) | MEN1KMT2AKDM4CGRM5 | |
| SCHEMBL10599277 | 0.81 | MEN1 (0.41) | MEN1KMT2AKDM4CL3MBTL1 | |
| SCHEMBL11813613 | 0.80 | MEN1 (0.35) | MEN1KMT2AKDM4CGRM5L3MBTL1 | |
| SCHEMBL2989785 | 0.80 | MEN1 (0.35) | MEN1KMT2AKDM4CGRM5L3MBTL1 | |
| SCHEMBL7533743 | 0.79 | MEN1 (0.35) | MEN1KMT2AKDM4CGRM5L3MBTL1 | |
| SCHEMBL10679266 | 0.79 | MEN1 (0.35) | MEN1KMT2AKDM4CGRM5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570594-B1 | HYDROXAMIC ACID DERIVATIVE BASED ON AROMATIC SULFONAMIDE | SHIONOGI & CO (JP) | 1997-07-30 | — | — | EP | disclosed |
| US-5534654-A | ANTITUMOR, ANTIINFLAMMATORY, INHIBITOR OF LYMPHOCYTE ADHESIVE FACTORS | SHIONOGI & CO., LTD. (JP) | 1996-07-09 | — | — | US | disclosed |
| EP-0570594-A1 | HYDROXAMIC ACID DERIVATIVE BASED ON AROMATIC SULFONAMIDE | SHIONOGI & CO., LTD. (JP) | 1993-11-24 | — | — | EP | disclosed |