Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769983 | 1.00 | SNCA (0.49) | SNCACYP2C9CYP2C19KMT2ASLC16A3 | |
| SCHEMBL8770040 | 0.81 | HDAC8 (0.56) | SNCACYP2C9CYP2C19KMT2ASLC16A3 | |
| SCHEMBL8770044 | 0.81 | HDAC8 (0.56) | SNCACYP2C9CYP2C19KMT2ASLC16A3 | |
| SCHEMBL8770106 | 0.80 | HDAC8 (0.55) | SNCACYP2C9CYP2C19KMT2ASLC16A3 | |
| SCHEMBL8770110 | 0.80 | HDAC8 (0.55) | SNCACYP2C9CYP2C19KMT2ASLC16A3 | |
| SCHEMBL8770041 | 0.80 | SNCA (0.54) | SNCACYP2C9CYP2C19KMT2ASLC16A3 | |
| SCHEMBL8770046 | 0.80 | SNCA (0.54) | SNCACYP2C9CYP2C19KMT2ASLC16A3 | |
| SCHEMBL8991797 | 0.80 | SNCA (0.54) | SNCACYP2C9CYP2C19KMT2ASLC16A3 | |
| SCHEMBL8120283 | 0.77 | SNCA (0.56) | SNCACYP2C9CYP2C19KMT2ASLC16A3 | |
| SCHEMBL8120286 | 0.77 | SNCA (0.56) | SNCACYP2C9CYP2C19KMT2ASLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570594-B1 | HYDROXAMIC ACID DERIVATIVE BASED ON AROMATIC SULFONAMIDE | SHIONOGI & CO (JP) | 1997-07-30 | — | — | EP | disclosed |
| US-5534654-A | ANTITUMOR, ANTIINFLAMMATORY, INHIBITOR OF LYMPHOCYTE ADHESIVE FACTORS | SHIONOGI & CO., LTD. (JP) | 1996-07-09 | — | — | US | disclosed |
| EP-0570594-A1 | HYDROXAMIC ACID DERIVATIVE BASED ON AROMATIC SULFONAMIDE | SHIONOGI & CO., LTD. (JP) | 1993-11-24 | — | — | EP | disclosed |