Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15145186 | 1.00 | PDE9A (0.64) | PDE9A | |
| SCHEMBL19725086 | 1.00 | PDE9A (0.64) | PDE9A | |
| SCHEMBL16445004 | 1.00 | PDE9A (0.64) | PDE9A | |
| SCHEMBL15142224 | 1.00 | PDE9A (0.64) | PDE9A | |
| SCHEMBL15279513 | 1.00 | PDE9A (0.64) | PDE9A | |
| Hydrochloric Acid SCHEMBL9932875 | 0.99 | PDE9A (0.62) | PDE9A | |
| SCHEMBL15266419 | 0.94 | PDE9A (0.57) | PDE9A | |
| SCHEMBL15279474 | 0.90 | PDE9A (0.56) | PDE9A | |
| SCHEMBL15151021 | 0.87 | PDE9A (0.64) | PDE9A | |
| Hydrochloric Acid SCHEMBL16445084 | 0.86 | PDE9A (0.63) | PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150045348-A1 | PDE9 inhibitors with imidazo triazinone backbone | H. LUNDBECK A/S (DK) | 2015-02-12 | — | — | US | claimed |
| EP-2807163-A1 | PDE9 INHIBITORS WITH IMIDAZO TRIAZINONE BACKBONE | H. Lundbeck A/S (DK) | 2014-12-03 | — | — | EP | claimed |
| WO-2013110768-A1 | PDE9 INHIBITORS WITH IMIDAZO TRIAZINONE BACKBONE | H. LUNDBECK A/S (DK) | 2013-08-01 | — | — | WO | claimed |
| US-9969742-B2 | Imidazotriazinone compounds | IRONWOOD PHARMACEUTICALS, INC. (US) | 2018-05-15 | — | — | US | disclosed |
| US-9969742-B2 | Imidazotriazinone compounds | IRONWOOD PHARMACEUTICALS, INC. (US) | 2018-05-15 | — | — | US | disclosed |
| US-9969742-B2 | Imidazotriazinone compounds | IRONWOOD PHARMACEUTICALS, INC. (US) | 2018-05-15 | — | — | US | disclosed |
| US-9850249-B2 | PDE9 inhibitors with imidazo triazinone backbone | H. LUNDBECK A/S (DK) | 2017-12-26 | — | — | US | disclosed |
| US-9850249-B2 | PDE9 inhibitors with imidazo triazinone backbone | H. LUNDBECK A/S (DK) | 2017-12-26 | — | — | US | disclosed |
| US-9850249-B2 | PDE9 inhibitors with imidazo triazinone backbone | H. LUNDBECK A/S (DK) | 2017-12-26 | — | — | US | disclosed |
| EP-3178820-B1 | PDE9- INHIBITORS WITH IMIDAZO TRIAZINONE BACKBONE | H LUNDBECK AS (DK) | 2017-12-20 | — | — | EP | disclosed |
| US-20170327502-A1 | IMIDAZOTRIAZINONE COMPOUNDS | IRONWOOD PHARMACEUTICALS INC (US) | 2017-11-16 | — | — | US | disclosed |
| WO-2013142269-A1 | IMIDAZOTRIAZINONE COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-09-26 | — | — | WO | disclosed |
| WO-2013110768-A1 | PDE9 INHIBITORS WITH IMIDAZO TRIAZINONE BACKBONE | H. LUNDBECK A/S (DK) | 2013-08-01 | — | — | WO | disclosed |
| WO-2013110768-A1 | PDE9 INHIBITORS WITH IMIDAZO TRIAZINONE BACKBONE | H. LUNDBECK A/S (DK) | 2013-08-01 | — | — | WO | disclosed |
| EP-2619208-A1 | IMIDAZOTRIAZINONE COMPOUNDS | Envivo Pharmaceuticals, Inc. (US) | 2013-07-31 | — | — | EP | disclosed |
| US-20120157458-A1 | IMIDAZOTRIAZINONE COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. | 2012-06-21 | — | — | US | disclosed |
| US-20120157458-A1 | IMIDAZOTRIAZINONE COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. | 2012-06-21 | — | — | US | disclosed |
| US-20120157458-A1 | IMIDAZOTRIAZINONE COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. | 2012-06-21 | — | — | US | disclosed |
| WO-2012040230-A1 | IMIDAZOTRIAZINONE COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012040230-A1 | IMIDAZOTRIAZINONE COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045348-A1 | PDE9 inhibitors with imidazo triazinone backbone | PDE9A, PDE5A, PDE12 | PDE9A 1/4885 |
| US-20170327502-A1 | IMIDAZOTRIAZINONE COMPOUNDS | PDE9A, PDE12, PDE4A | PDE9A 1/4885 |
| US-20120157458-A1 | IMIDAZOTRIAZINONE COMPOUNDS | PDE9A, PDE4A, PDE12 | PDE9A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.