SCHEMBL877031

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL683345	1.00	NR1H2 (0.38)	NR1H2NR1H3CCR5CCR1ABCB1
	SCHEMBL877553	0.92	NR1H2 (0.38)	NR1H2NR1H3CCR5CCR1ABCB1
	SCHEMBL683353	0.92	NR1H2 (0.38)	NR1H2NR1H3CCR5CCR1ABCB1
	SCHEMBL2139543	0.91	NR1H2 (0.39)	NR1H2NR1H3CCR1ABCB1HCRTR1
	SCHEMBL683393	0.91	NR1H2 (0.39)	NR1H2NR1H3CCR1ABCB1HCRTR1
	SCHEMBL877084	0.90	NR1H2 (0.40)	NR1H2NR1H3CCR1ALKCHRM4
	SCHEMBL683019	0.90	NR1H2 (0.40)	NR1H2NR1H3CCR1ALKCHRM4
	SCHEMBL682708	0.89	PDE4B (0.41)	NR1H2NR1H3CCR1
	SCHEMBL876544	0.89	PDE4B (0.41)	NR1H2NR1H3CCR1
	SCHEMBL877190	0.87	NR1H2 (0.39)	NR1H2NR1H3CCR5CCR1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.