Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771113 | 1.00 | NR1I2 (0.49) | NR1I2CA5AMAPTTDP1CYP3A4 | |
| SCHEMBL8943520 | 0.89 | MAPK1 (0.56) | NR1I2MAPTTDP1CYP3A4HSD17B10 | |
| SCHEMBL3836105 | 0.89 | MAPK1 (0.56) | NR1I2MAPTTDP1CYP3A4HSD17B10 | |
| SCHEMBL3836103 | 0.89 | MAPK1 (0.56) | NR1I2MAPTTDP1CYP3A4HSD17B10 | |
| SCHEMBL18023724 | 0.89 | MAPK1 (0.56) | NR1I2MAPTTDP1CYP3A4HSD17B10 | |
| SCHEMBL8943516 | 0.89 | MAPK1 (0.56) | NR1I2MAPTTDP1CYP3A4HSD17B10 | |
| SCHEMBL11333355 | 0.86 | CTDSP1 (0.49) | NR1I2MAPTTDP1CYP3A4HSD17B10 | |
| SCHEMBL11333366 | 0.86 | CTDSP1 (0.49) | NR1I2MAPTTDP1CYP3A4HSD17B10 | |
| SCHEMBL8770963 | 0.86 | HSD17B10 (0.41) | NR1I2MAPTTDP1CYP3A4HSD17B10 | |
| SCHEMBL8770979 | 0.86 | HSD17B10 (0.41) | NR1I2MAPTTDP1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796263-A1 | CEPHEM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996017850-A1 | CEPHEM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-13 | — | — | WO | disclosed |