Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453970 | 1.00 | USP5 (0.34) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL2847049 | 1.00 | USP5 (0.34) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL12975983 | 0.98 | USP5 (0.34) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL12975888 | 0.98 | USP5 (0.34) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL17070829 | 0.95 | HTR2A (0.37) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL20219125 | 0.94 | GRIA4 (0.33) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL12975904 | 0.93 | USP5 (0.32) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL12975931 | 0.93 | USP5 (0.32) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL12975873 | 0.93 | USP5 (0.32) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL12975893 | 0.93 | USP5 (0.32) | USP5HDAC6HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799878-A1 | Liquid crystal compositions and liquid crystal display elements containing same | Shin-Etsu Chemical Co., Ltd. (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5185098-A | Liquid crystalline mixtures containing 3,4-difluorophenyl-substituted bicyclohexyls | HOFFMANN-LA ROCHE INC. (US) | 1993-02-09 | — | — | US | disclosed |