Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.66 |
| ▸ | HTR2A | P28223 | 9/20 | 0.56 |
| ▸ | HTR2C | P28335 | 6/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.53 |
| ▸ | HTR7 | P34969 | 3/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7808526 | 0.99 | HTR2B (0.68) | HTR2BHTR2AHTR2CGRIN2BCHRM4 | |
| Hydrochloric Acid SCHEMBL7808130 | 0.85 | HTR2B (0.61) | HTR2BHTR2AHTR2CGRIN2BCHRM4 | |
| SCHEMBL7808486 | 0.84 | HTR2B (0.72) | HTR2BHTR2AHTR2CGRIN2BCHRM4 | |
| SCHEMBL7822460 | 0.84 | HTR2B (0.72) | HTR2BHTR2AHTR2CGRIN2BCHRM4 | |
| Hydrochloric Acid SCHEMBL7816888 | 0.83 | HTR2B (0.74) | HTR2BHTR2AHTR2CGRIN2BCHRM4 | |
| Hydrochloric Acid SCHEMBL7816431 | 0.83 | HTR2B (0.74) | HTR2BHTR2AHTR2CGRIN2BCHRM4 | |
| SCHEMBL29462336 | 0.81 | HTR2B (0.98) | HTR2BHTR2ACHRM4HTR7DRD2 | |
| SCHEMBL11043054 | 0.81 | HTR2B (0.98) | HTR2BHTR2ACHRM4HTR7DRD2 | |
| SCHEMBL9391684 | 0.81 | HTR2B (0.98) | HTR2BHTR2ACHRM4HTR7DRD2 | |
| Hydrochloric Acid SCHEMBL6087920 | 0.80 | HTR2B (0.60) | HTR2BHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797994-A2 | Use of one or more 5-HT2 receptor antagonists in the manufacture of a medicament for treating the symptoms of venomous bites and stings | ELI LILLY AND COMPANY (US) | 1997-10-01 | — | — | EP | disclosed |