Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665790 | 0.89 | KMT2A (0.46) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL1665304 | 0.86 | ABL1 (0.45) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL13964566 | 0.82 | KMT2A (0.39) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL13964567 | 0.77 | KMT2A (0.42) | KMT2ARAB9AEPHX2 | |
| SCHEMBL13964564 | 0.77 | F2 (0.41) | KMT2AMEN1SMN1; SMN2EPHX2 | |
| SCHEMBL1664406 | 0.75 | NPC1 (0.53) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8771742 | 0.74 | TNIK (0.51) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL1666784 | 0.73 | SMYD3 (0.46) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL1664229 | 0.73 | MAOB (0.50) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL1664647 | 0.73 | MAOB (0.53) | KMT2AMAPTMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068406-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2012-05-24 | — | — | WO | disclosed |