Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 4/20 | 0.31 |
| ▸ | GABRD | O14764 | 4/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10589745 | 0.75 | — | — | |
| Acetic Acid SCHEMBL4807645 | 0.75 | — | — | |
| SCHEMBL7523366 | 0.73 | — | — | |
| Acetic Acid SCHEMBL27717337 | 0.72 | FFAR3 (0.58) | FFAR3LCKFYNLMNAMAPT | |
| Acetic Acid SCHEMBL670655 | 0.72 | FFAR3 (0.58) | FFAR3LCKFYNLMNAMAPT | |
| Acetic Acid SCHEMBL28157960 | 0.72 | — | — | |
| Acetic Acid SCHEMBL9151775 | 0.72 | FFAR3 (0.58) | FFAR3LCKFYNLMNAMAPT | |
| Acetic Acid SCHEMBL44094 | 0.72 | — | — | |
| Acetic Acid SCHEMBL4292108 | 0.69 | FFAR3 (0.54) | FFAR3LCKFYNLMNASLC7A5 | |
| Acetic Acid SCHEMBL18813849 | 0.69 | FFAR3 (0.54) | FFAR3LCKFYNLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621507-B1 | Colour development composition and processing method using composition | CHUGAI SHASHIN YAKUHIN (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5466565-A | Color development composition and process | CHUGAI PHOTE CHEMICAL CO., LTD. (JP) | 1995-11-14 | — | — | US | disclosed |
| EP-0621507-A1 | Colour development composition and processing method using composition | CHUGAI PHOTO CHEMICAL CO. LTD. (JP) | 1994-10-26 | — | — | EP | disclosed |