⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19909459 | 0.62 | — | — | |
| SCHEMBL2041924 | 0.62 | — | — | |
| SCHEMBL1291106 | 0.60 | — | — | |
| SCHEMBL19011612 | 0.58 | — | — | |
| SCHEMBL7835303 | 0.52 | — | — | |
| SCHEMBL13721252 | 0.51 | — | — | |
| SCHEMBL22592092 | 0.48 | — | — | |
| SCHEMBL21947378 | 0.40 | — | — | |
| SCHEMBL4356623 | 0.40 | — | — | |
| SCHEMBL17935692 | 0.39 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102171205-B | Pyrazinone modulators of corticotropin releasing factor receptor activity | BRISTOL MYERS SQUIBB CO | 2013-08-07 | — | — | CN | claimed |
| EP-4257131-A2 | PYRIDIN-2(1H)-ONE QUINOLINONE DERIVATIVES AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS | Forma Therapeutics, Inc. (US) | 2023-10-11 | — | — | EP | disclosed |
| CN-102171205-B | Pyrazinone modulators of corticotropin releasing factor receptor activity | BRISTOL MYERS SQUIBB CO | 2013-08-07 | — | — | CN | disclosed |
| CN-102171205-A | Pyrazinone modulators of corticotropin releasing factor receptor activity | BRISTOL MYERS SQUIBB CO | 2011-08-31 | — | — | CN | disclosed |
| EP-0799211-A1 | 2-CARBAMOYL-1,4,5,6-TETRAHYDROPYRAZINES | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-08 | — | — | EP | disclosed |