Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPC | P11150 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776909 | 1.00 | TRPV1 (0.49) | TRPV1LMNATSHRHPGDALDH1A1 | |
| SCHEMBL8441538 | 0.87 | TRPV1 (0.49) | TRPV1LMNATSHRHPGDALDH1A1 | |
| SCHEMBL8440268 | 0.82 | KMT2A (0.44) | TRPV1LMNAKMT2AL3MBTL1ASAH1 | |
| SCHEMBL8440271 | 0.82 | KMT2A (0.44) | TRPV1LMNAKMT2AL3MBTL1ASAH1 | |
| SCHEMBL8439464 | 0.80 | KMT2A (0.43) | TRPV1LMNAKMT2AASAH1LPL | |
| SCHEMBL27495124 | 0.80 | TRPV1 (0.50) | TRPV1LMNATSHRHPGDALDH1A1 | |
| SCHEMBL27476952 | 0.80 | TRPV1 (0.50) | TRPV1LMNATSHRHPGDALDH1A1 | |
| SCHEMBL8440276 | 0.80 | TRPV1 (0.50) | TRPV1LMNATSHRHPGDALDH1A1 | |
| SCHEMBL8440280 | 0.80 | TRPV1 (0.50) | TRPV1LMNATSHRHPGDALDH1A1 | |
| SCHEMBL8441268 | 0.80 | TRPV1 (0.50) | TRPV1LMNATSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799200-A1 | SUBSTITUTED AZETIDIN-2-ONES FOR TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |