Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 5/20 | 0.52 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 9/20 | 0.45 |
| ▸ | MMP3 | P08254 | 7/20 | 0.45 |
| ▸ | MMP1 | P03956 | 6/20 | 0.45 |
| ▸ | MMP9 | P14780 | 4/20 | 0.45 |
| ▸ | MMP7 | P09237 | 3/20 | 0.45 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597388 | 0.79 | FOLH1 (0.59) | BIRC2MMP2MMP3MMP1MMP9 | |
| SCHEMBL8269110 | 0.78 | MME (0.61) | BIRC2MMEMMP2MMP3MMP1 | |
| SCHEMBL19818899 | 0.74 | PLA2G2C (0.54) | PLA2G10PLA2G2C | |
| SCHEMBL21141384 | 0.74 | PLA2G2C (0.54) | PLA2G10PLA2G2C | |
| SCHEMBL2831336 | 0.74 | GRIK1 (0.68) | — | |
| SCHEMBL1411995 | 0.74 | GRIK1 (0.68) | — | |
| SCHEMBL2833540 | 0.74 | GRIK1 (0.68) | — | |
| SCHEMBL1871699 | 0.74 | GRIK1 (0.68) | — | |
| SCHEMBL2835497 | 0.74 | GRIK1 (0.68) | — | |
| SCHEMBL2831405 | 0.74 | GRIK1 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800510-A1 | HYDROXAMIC ACID-CONTAINING INHIBITORS OF MATRIX METALLOPROTEASES | THE PROCTER & GAMBLE COMPANY (US) | 1997-10-15 | — | — | EP | claimed |
| US-5639746-A | INHIBITORS OF METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-17 | — | — | US | claimed |
| WO-1996020918-A1 | HYDROXAMIC ACID-CONTAINING INHIBITORS OF MATRIX METALLOPROTEASES | THE PROCTER & GAMBLE COMPANY (US) | 1996-07-11 | — | — | WO | claimed |
| US-5639746-A | INHIBITORS OF METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-17 | — | — | US | disclosed |