SCHEMBL8773307

SCHEMBL8773307

CN1CCN(C)C(=O)N(C)CC1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.38
BRD2 P25440 1/20 0.38
CYP1A2 P05177 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.34
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
POLB P06746 1/20 0.32
NEK2 P51955 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2398125 0.90 BRD4 (0.43) BRD4BRD2KMT2A
SCHEMBL3043 0.90
Ethane SCHEMBL28172818 0.87 BRD4 (0.41) BRD4BRD2KMT2A
Hydrochloric Acid SCHEMBL9336582 0.87
SCHEMBL27822918 0.87
Lithium SCHEMBL31009372 0.87
Fluoride SCHEMBL6368967 0.87 BRD4 (0.41) BRD4BRD2KMT2A
Fluoride SCHEMBL28881930 0.87 BRD4 (0.41) BRD4BRD2KMT2A
Water SCHEMBL3778195 0.87
Fluoride SCHEMBL15910775 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8048891-A None JP disclosed
JP-8067823-A None JP disclosed
JP-7291949-A None JP disclosed
CN-1105713-C Process for the production of dianthraquinone-N,N'-dihydroazine MITSUI CHEMICALS INC (JP) 2003-04-16 CN disclosed
EP-0670316-B1 1,3,6-Trialkylhexahydro-1,3,6-triazocine-2-one and preparation process thereof MITSUI TOATSU CHEMICALS (JP) 1997-09-03 EP disclosed
US-5514793-A 1,3,6-trialkylhexahydro-1,3,6-triazocine-2-on and preparation process thereof MITSUI TOATSU CHEMICALS, INC. (JP) 1996-05-07 US disclosed
JP-H0867823-A PRODUCTION OF DIANTHRAQUINONE-N, N'-DIHYDROAZINE MITSUI TOATSU CHEM INC 1996-03-12 JP disclosed
JP-H0848891-A PRODUCTION OF DIANTHRAQUINONE-N,N'-DIHYDROAZINE MITSUI TOATSU CHEM INC 1996-02-20 JP disclosed
JP-H07291949-A 1,3,6-TRIALKYLHEXAHYDRO-1,3,6-TRIAZOCIN-2-ONE AND PRODUCTION THEREOF MITSUI TOATSU CHEM INC 1995-11-07 JP disclosed
EP-0670316-A1 1,3,6-Trialkylhexahydro-1,3,6-triazocine-2-one and preparation process thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-09-06 EP disclosed