SCHEMBL8773591

SCHEMBL8773591

CC(C)Oc1cccc(P)c1OC(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.40
IRAK4 Q9NWZ3 2/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
ALDH1A1 P00352 2/20 0.37
ACHE P22303 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
HTR1A P08908 2/20 0.34
HTR1D P28221 2/20 0.34
HTR2C P28335 2/20 0.34
HTR7 P34969 2/20 0.34
HTR5A P47898 2/20 0.34
MEN1 O00255 1/20 0.34
POLB P06746 1/20 0.34
KMT2A Q03164 1/20 0.34
GRM5 P41594 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2069873 0.84 MCHR1 (0.46) MCHR1IRAK4CA1CA2CA7
SCHEMBL28347159 0.83 CA1 (0.40) MCHR1IRAK4CA1CA2CA7
SCHEMBL10445521 0.80 IRAK4 (0.47) MCHR1IRAK4CA1CA2CA7
Cyclohexane SCHEMBL28914248 0.79 CA1 (0.37) MCHR1IRAK4CA1CA2CA7
SCHEMBL31734646 0.78 MCHR1 (0.44) MCHR1IRAK4CA1CA2CA7
SCHEMBL8970180 0.77 MCHR1 (0.45) MCHR1NPSR1MEN1KMT2AKDM4E
SCHEMBL2400561 0.77 MCHR1 (0.41) MCHR1IRAK4CA1CA2CA7
SCHEMBL19612192 0.77 SMN1; SMN2 (0.47) MCHR1IRAK4CA1CA2CA7
SCHEMBL16606241 0.77 SCN4A (0.42) MCHR1IRAK4CA1CA2CA7
SCHEMBL17912820 0.76 NPSR1 (0.46) MCHR1IRAK4CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5696304-A REACTING CONJUGATED ALKADIENOL WITH WATER USING PALLADIUM CATALYST IN LOW BOILING REACTION SOLVENT, THEN DISTILLATION MITSUBISHI CHEMICAL CORPORATION (JP) 1997-12-09 US disclosed
EP-0605735-B1 PROCESS FOR PRODUCING ALKADIENOL MITSUBISHI CHEM CORP (JP) 1997-11-05 EP disclosed
US-5557016-A HYDROXYLATION OF CONJUGATED ALKADIENES IN THE PRESENCE OF PALLADIUM CATALYSIS MITSUBISHI KASEI CORPORATION (JP) 1996-09-17 US disclosed
EP-0361304-B1 Method for producing alkadienols MITSUBISHI CHEM CORP (JP) 1996-02-21 EP disclosed
EP-0605735-A1 PROCESS FOR PRODUCING ALKADIENOL Mitsubishi Chemical Corporation (JP) 1994-07-13 EP disclosed
US-4990698-A Method for producing alkadienols MITSUBISHI KASEI CORPORATION (JP) 1991-02-05 US disclosed
US-4324744-A PHOTOINITIATORS BASF AKTIENGESELLSCHAFT (DE) 1982-04-13 US disclosed
US-4265723-A UNSATURATED POLYESTERS OR VINYL ESTERS OF POLYEPOXIDES AND A UV SENSITIZER OF AN ACYL PHOSPHINE OXIDE BASF AKTIENGESELLSCHAFT (DE) 1981-05-05 US disclosed
US-3992456-A BY REACTING BUTADIENE WITH WATER IN THE PRESENCE OF A PALLADIUM CATALYST UNION CARBIDE CORPORATION (US) 1976-11-16 US disclosed