Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1612645 | 0.83 | PNP (0.56) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5347880 | 0.83 | PNP (0.56) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5360845 | 0.82 | CYP1A2 (0.71) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL20165850 | 0.81 | PNP (0.64) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL10446997 | 0.81 | PNP (0.64) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL23647921 | 0.81 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL7199411 | 0.81 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL28156309 | 0.81 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL3707304 | 0.81 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL17521212 | 0.81 | PNP (0.62) | PNPLMNATP53HTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644196-B1 | TTTr as a protecting group in nucleotide synthesis | CIBA GEIGY AG (CH) | 1997-11-05 | — | — | EP | disclosed |
| EP-0644196-A1 | TTTr as a protecting group in nucleotide synthesis | CIBA-GEIGY AG (CH) | 1995-03-22 | — | — | EP | disclosed |