SCHEMBL8773630

SCHEMBL8773630

CC(C)C[C@H](N)C(=O)N(C[C]=O)C(=O)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.36
CTSL P07711 1/20 0.32
CTSB P07858 1/20 0.32
CTSS P25774 1/20 0.32
CTSK P43235 1/20 0.32
AAK1 Q2M2I8 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10953721 0.81 SLC7A5 (0.41) SLC7A5CTSLCTSBCTSSCTSK
SCHEMBL28195149 0.81 SLC7A5 (0.41) SLC7A5CTSLCTSBCTSSCTSK
SCHEMBL8693203 0.80 SLC7A5 (0.36) SLC7A5AAK1
SCHEMBL28916811 0.79 SLC7A5 (0.35) SLC7A5CTSLCTSBCTSSCTSK
SCHEMBL10339672 0.78 HDAC6 (0.37) CTSLCTSBCTSSCTSK
SCHEMBL7349668 0.77 GRIK1 (0.35) SLC7A5CTSKAAK1
SCHEMBL5731119 0.75 HDAC6 (0.33)
SCHEMBL5438062 0.74 CA14 (0.34) SLC7A5AAK1
SCHEMBL7775531 0.74 SLC7A5 (0.31) SLC7A5
SCHEMBL7747137 0.73 HDAC6 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805161-A1 (1$m(7)3)-$g(b)-D-GLUCAN-BINDING PROTEIN, ANTIBODY THAT RECOGNIZES THE PROTEIN, AND USE OF THE PROTEIN AND ANTIBODY SEIKAGAKU CORPORATION (JP) 1997-11-05 EP disclosed