SCHEMBL8773659

SCHEMBL8773659

CC(C)(C)N(NC(=O)c1ccccc1)C(=O)c1ccccc1Br

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.70
CYP3A4 P08684 1/20 0.65
CYP2C9 P11712 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10718314 0.91 POLB (0.57) POLB
SCHEMBL10719304 0.90 ABCB1 (0.56) POLB
SCHEMBL10720068 0.89 ABCB1 (0.58)
Hydrochloric Acid SCHEMBL8166396 0.89 POLB (0.56) POLB
SCHEMBL9714356 0.89 POLB (0.70) POLBCYP3A4CYP2C9
Hydrochloric Acid SCHEMBL8173905 0.88 ABCB1 (0.57)
SCHEMBL10721386 0.87 POLB (0.63) POLBCYP3A4CYP2C9
Hydrochloric Acid SCHEMBL8165727 0.86 HPGD (0.68) CYP3A4
SCHEMBL9714286 0.86 POLB (0.52) POLB
SCHEMBL9714513 0.86 POLB (0.52) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0630568-B1 Method of controlling insects ROHM & HAAS (US) 1997-09-10 EP claimed
EP-0630568-A1 Method of controlling insects ROHM AND HAAS COMPANY (US) 1994-12-28 EP claimed
US-5358966-A Using n,n'-diacylhydrazine ROHM AND HAAS COMPANY (US) 1994-10-25 US claimed
US-4985461-A Insecticidal N'-substituted-N,N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1991-01-15 US claimed
EP-0630568-B1 Method of controlling insects ROHM & HAAS (US) 1997-09-10 EP disclosed
EP-0630568-A1 Method of controlling insects ROHM AND HAAS COMPANY (US) 1994-12-28 EP disclosed
US-5358966-A Using n,n'-diacylhydrazine ROHM AND HAAS COMPANY (US) 1994-10-25 US disclosed
EP-0245950-B1 INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1992-06-17 EP disclosed
EP-0236618-B1 INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1991-02-27 EP disclosed
US-4985461-A Insecticidal N'-substituted-N,N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1991-01-15 US disclosed
EP-0236618-A2 Insecticidal N'-substituted-N,N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1987-09-16 EP disclosed