SCHEMBL8773745

SCHEMBL8773745

c1ccc(Cc2ccccc2OCCN2CCCCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 8/20 1.00
DRD1 P21728 6/20 1.00
DRD5 P21918 5/20 1.00
DRD4 P21917 4/20 1.00
DRD3 P35462 4/20 1.00
DRD2 P14416 3/20 1.00
LTA4H P09960 7/20 0.65
TDP1 Q9NUW8 1/20 0.61
TSHR P16473 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6394664 0.93 HRH1 (1.00) HRH1DRD1DRD5DRD4DRD3
SCHEMBL11630424 0.92 HRH1 (0.92) HRH1DRD1DRD5DRD4DRD3
SCHEMBL7397541 0.90 HRH1 (0.90) HRH1DRD1DRD5DRD4DRD3
Hydrochloric Acid SCHEMBL7399800 0.89 HRH1 (0.87) HRH1DRD1DRD5DRD4DRD3
SCHEMBL11251197 0.87 HRH1 (0.77) HRH1DRD1DRD5DRD4DRD3
SCHEMBL28870126 0.87 HRH1 (0.79) HRH1DRD1DRD5DRD4DRD3
SCHEMBL30023614 0.87 HRH1 (0.79) HRH1DRD1DRD5DRD4DRD3
Hydrochloric Acid SCHEMBL25430139 0.86 HRH1 (0.77) HRH1DRD1DRD5DRD4DRD3
SCHEMBL5751156 0.86 HRH1 (0.77) HRH1DRD1DRD5DRD4DRD3
Hydrochloric Acid SCHEMBL30023580 0.86 HRH1 (0.77) HRH1DRD1DRD5DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4212512-A1 PREPARATION METHOD FOR HIGH PURITY 1-(1-(2-BENZYL PHENOXY)PROPAN-2-YL)-2-METHYLPIPERIDINE SINGLE ISOMER VSpharmtech Inc. (KR) 2023-07-19 EP disclosed
WO-2023101115-A1 PREPARATION METHOD FOR HIGH PURITY 1-(1-(2-BENZYL PHENOXY)PROPAN-2-YL)-2-METHYLPIPERIDINE SINGLE ISOMER 주식회사 브이에스팜텍 2023-06-08 WO disclosed
EP-0804427-A1 LTA4 HYDROLASE INHIBITORS G.D. SEARLE & CO. (US) 1997-11-05 EP disclosed
WO-1996011192-A1 LTA4 HYDROLASE INHIBITORS G.D. SEARLE & CO. (US) 1996-04-18 WO disclosed