Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.75 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848215 | 0.88 | TLR7 (0.81) | TLR7 | |
| SCHEMBL2845663 | 0.88 | TLR7 (0.78) | TLR7 | |
| SCHEMBL30035871 | 0.88 | TLR7 (0.81) | TLR7 | |
| SCHEMBL3701182 | 0.86 | TLR7 (0.71) | TLR7 | |
| SCHEMBL29447438 | 0.86 | TLR7 (1.00) | TLR7 | |
| SCHEMBL15392126 | 0.86 | TLR7 (1.00) | TLR7 | |
| SCHEMBL4211013 | 0.86 | TLR7 (0.74) | TLR7 | |
| SCHEMBL30037348 | 0.86 | TLR7 (0.74) | TLR7 | |
| SCHEMBL2846137 | 0.86 | TLR7 (0.86) | TLR7 | |
| SCHEMBL2849272 | 0.86 | TLR7 (1.00) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066336-A1 | BENZYLAMINE COMPOUNDS AS TOLL -LIKE RECEPTOR 7 AGONISTS | ASTRAZENECA AB (SE) | 2012-05-24 | — | — | WO | disclosed |