SCHEMBL877411

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL683021	1.00	NR1H2 (0.38)	NR1H2NR1H3HCRTR1CCR5PTGDR
	SCHEMBL682987	0.90	PDE4B (0.39)	NR1H2NR1H3HCRTR1
	SCHEMBL683338	0.90	PDE4B (0.40)	NR1H2NR1H3
	SCHEMBL876994	0.90	PDE4B (0.40)	NR1H2NR1H3
	SCHEMBL2137872	0.90	PDE4B (0.39)	NR1H2NR1H3HCRTR1
	SCHEMBL877423	0.86	PDE4B (0.36)	NR1H2NR1H3HCRTR1KMT2A
	SCHEMBL683355	0.85	NR1H2 (0.40)	NR1H2NR1H3ALDH1A1ABCB1ALK
	SCHEMBL876882	0.85	NR1H2 (0.40)	NR1H2NR1H3ALDH1A1ABCB1ALK
	SCHEMBL683023	0.85	NR1H2 (0.43)	NR1H2NR1H3HCRTR1CCR5PTGDR
	SCHEMBL2138237	0.85	NR1H2 (0.43)	NR1H2NR1H3HCRTR1CCR5PTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.