Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774426 | 1.00 | PDGFRB (0.39) | PDGFRBPDGFRAMAOAMAOBHRH3 | |
| SCHEMBL8774443 | 0.96 | PDGFRB (0.37) | PDGFRBPDGFRA | |
| SCHEMBL8774462 | 0.96 | PDGFRB (0.37) | PDGFRBPDGFRA | |
| SCHEMBL8774452 | 0.96 | PDGFRB (0.37) | PDGFRBPDGFRA | |
| SCHEMBL8774436 | 0.96 | PDGFRB (0.37) | PDGFRBPDGFRA | |
| SCHEMBL8774902 | 0.91 | PDGFRB (0.38) | PDGFRBPDGFRAMAOAMAOBHRH3 | |
| SCHEMBL8774893 | 0.91 | PDGFRB (0.38) | PDGFRBPDGFRAMAOAMAOBHRH3 | |
| SCHEMBL8774315 | 0.91 | PDGFRB (0.39) | PDGFRBPDGFRAMAOAMAOB | |
| SCHEMBL8774325 | 0.91 | PDGFRB (0.39) | PDGFRBPDGFRAMAOAMAOB | |
| SCHEMBL8774554 | 0.90 | PDGFRB (0.37) | PDGFRBPDGFRAHRH3PKMCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |