Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | CDC25B | P30305 | 5/20 | 0.46 |
| ▸ | CDC25A | P30304 | 2/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775421 | 1.00 | HPSE (0.54) | HPSECES2MAOBCDC25BCDC25A | |
| SCHEMBL8775103 | 1.00 | HPSE (0.54) | HPSECES2MAOBCDC25BCDC25A | |
| SCHEMBL8775197 | 0.88 | HPSE (0.48) | HPSEMAOBCDC25BCDC25ADUSP3 | |
| SCHEMBL8775107 | 0.88 | HPSE (0.48) | HPSEMAOBCDC25BCDC25ADUSP3 | |
| SCHEMBL8775118 | 0.88 | HPSE (0.48) | HPSEMAOBCDC25BCDC25ADUSP3 | |
| SCHEMBL8775124 | 0.88 | HPSE (0.48) | HPSEMAOBCDC25BCDC25ADUSP3 | |
| SCHEMBL8775207 | 0.88 | HPSE (0.48) | HPSEMAOBCDC25BCDC25ADUSP3 | |
| SCHEMBL7984845 | 0.83 | HPSE (0.44) | HPSEMAOBCDC25BCDC25ADUSP3 | |
| SCHEMBL7972796 | 0.82 | HPSE (0.40) | HPSEMAOB | |
| SCHEMBL13486530 | 0.82 | HPSE (0.52) | HPSECES2MAOBCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804430-A1 | SYNTHESIS OF OPTICALLY PURE 4-ALKENYL- OR 4-ALKANYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1997-11-05 | — | — | EP | disclosed |
| US-5656662-A | TREATING OR PREVENTING ATHEROSCLEROTIC DISORDERS, INHIBITING INFLAMMATORY CYTOKINES | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1997-08-12 | — | — | US | disclosed |
| US-5504107-A | ANTICOAGULANTS, PREVENTING ATHEROSCLEROSIS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1995032194-A1 | SYNTHESIS OF OPTICALLY PURE 4-ALKENYL- OR 4-ALKANYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1995-11-30 | — | — | WO | disclosed |