SCHEMBL8775453

SCHEMBL8775453

C1COC2(CC2)CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL16011958 0.97
SCHEMBL459200 0.90 SLC6A2 (0.39)
SCHEMBL16877358 0.90 SLC6A2 (0.39)
SCHEMBL8775578 0.90
SCHEMBL785589 0.90 SLC6A2 (0.39)
SCHEMBL31616178 0.89 SLC6A2 (0.38)
Hydrochloric Acid SCHEMBL17667895 0.87 SLC6A2 (0.38)
SCHEMBL16878543 0.87 SLC6A2 (0.38)
SCHEMBL8751060 0.87 SLC6A2 (0.38)
SCHEMBL5423705 0.86 SLC6A2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4568960-B1 BICYCLIC TETRAHYDROAZEPINE DERIVATIVES HOFFMANN LA ROCHE (CH) 2026-04-29 EP claimed
US-12435068-B2 Anthelmintic compounds ELANCO ANIMAL HEALTH GMBH (DE) 2025-10-07 US claimed
US-12391682-B2 Isoquinoline derivatives and their use for the treatment of parasitic infections ELANCO ANIMAL HEALTH GMBH (DE) 2025-08-19 US claimed
EP-4003524-B1 ISOQUINOLINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARASITIC INFECTIONS ELANCO ANIMAL HEALTH GMBH (DE) 2025-04-09 EP claimed
EP-3634959-B1 QUINOLINE DERIVATIVES FOR TREATING INFECTIONS WITH HELMINTHS ELANCO ANIMAL HEALTH GMBH (DE) 2025-02-26 EP claimed
CN-119409690-A Novel insect repellent compound 拜耳动物保健有限责任公司 2025-02-11 CN claimed
CN-119101009-A Preparation method of 4-oxa-7-azaspiro [2.5] octane 南京药石科技股份有限公司 2024-12-10 CN claimed
EP-4448105-A1 HETEROCYCLE DERIVATIVES FOR THE TREATMENT OF DISEASE VIR Biotechnology, Inc. (US) 2024-10-23 EP claimed
WO-2024213752-A1 LONG-TERM PREVENTION AND/OR TREATMENT OF A DISEASE BY SLO-1 INHIBITORS ELANCO ANIMAL HEALTH GMBH (DE) 2024-10-17 WO claimed
CN-114423749-B Isoquinoline derivatives and their use for the treatment of parasitic infections 拜耳动物保健有限责任公司 2024-10-01 CN claimed
US-20200190111-A1 NEW BICYCLIC PYRAZOLE DERIVATIVES BAYER ANIMAL HEALTH GMBH (DE) 2020-06-18 US claimed
US-20200131175-A1 NEW AZAQUINOLINE DERIVATIVES BAYER ANIMAL HEALTH GMBH (DE) 2020-04-30 US claimed
EP-3643711-A1 NEW ANTHELMINTIC COMPOUNDS Bayer Animal Health GmbH (DE) 2020-04-29 EP claimed
EP-3634959-A1 QUINOLINE DERIVATIVES FOR TREATING INFECTIONS WITH HELMINTHS Bayer Animal Health GmbH (DE) 2020-04-15 EP claimed
EP-3615527-A1 NEW AZAQUINOLINE DERIVATIVES Bayer Animal Health GmbH (DE) 2020-03-04 EP claimed
EP-3538512-A1 NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES Bayer Animal Health GmbH (DE) 2019-09-18 EP claimed
WO-2019025341-A1 QUINOLINE DERIVATIVES FOR TREATING INFECTIONS WITH HELMINTHS BAYER ANIMAL HEALTH GMBH (DE) 2019-02-07 WO claimed
WO-2019002132-A1 NEW AZAQUINOLINE DERIVATIVES BAYER ANIMAL HEALTH GMBH (DE) 2019-01-03 WO claimed
WO-2018197401-A1 NEW BICYCLIC PYRAZOLE DERIVATIVES BAYER ANIMAL HEALTH GMBH (DE) 2018-11-01 WO claimed
WO-2018087036-A1 NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES BAYER ANIMAL HEALTH GMBH (DE) 2018-05-17 WO claimed