SCHEMBL8776396

SCHEMBL8776396

CC(C)CC(NC(=O)C(N)Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 8/20 0.70
ERAP2 Q6P179 4/20 0.66
ACE P12821 2/20 0.65
KDM4E B2RXH2 1/20 0.64
MEN1 O00255 1/20 0.64
LMNA P02545 1/20 0.64
MPO P05164 1/20 0.64
MAPT P10636 1/20 0.64
TSHR P16473 1/20 0.64
BLM P54132 1/20 0.64
PMP22 Q01453 1/20 0.64
KMT2A Q03164 1/20 0.64
HIF1A Q16665 1/20 0.64
ERAP1 Q9NZ08 3/20 0.60
IL1RN P18510 2/20 0.60
MMP2 P08253 2/20 0.59
MMP9 P14780 1/20 0.59
MMP8 P22894 1/20 0.59
MMP1 P03956 1/20 0.59
TP53 P04637 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29794195 1.00 ECE1 (0.70) ECE1ERAP2ACEKDM4EMEN1
SCHEMBL7622341 1.00 ECE1 (0.70) ECE1ERAP2ACEKDM4EMEN1
SCHEMBL7622335 1.00 ECE1 (0.70) ECE1ERAP2ACEKDM4EMEN1
SCHEMBL29352768 1.00 ECE1 (0.70) ECE1ERAP2ACEKDM4EMEN1
SCHEMBL30991071 1.00 ECE1 (0.70) ECE1ERAP2ACEKDM4EMEN1
SCHEMBL29538468 0.98 ERAP2 (0.69) ECE1ERAP2ACEKDM4EMEN1
SCHEMBL30051905 0.97 ECE1 (0.69) ECE1ERAP2ACEKDM4EMEN1
SCHEMBL30051545 0.96 ECE1 (0.65) ECE1ERAP2ACEKDM4EMEN1
SCHEMBL29987530 0.95 ECE1 (0.64) ECE1ERAP2ACEKDM4EMEN1
SCHEMBL30051546 0.95 ERAP2 (0.73) ECE1ERAP2ACEERAP1IL1RN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3604503-B1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO KK (JP) 2026-03-18 EP disclosed
US-20250270512-A1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO CO., INC. (JP) 2025-08-28 US disclosed
CN-110494559-B Culture medium additive for non-differentiation maintenance 味之素株式会社 2023-10-31 CN disclosed
WO-2020117099-A1 DIPEPTIDE LIGANDS OF TSPO THAT POSSESS NEUROPSYCHOTROPIC ACTIVITY Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова" 2020-06-11 WO disclosed
US-20200040308-A1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO CO., INC. (JP) 2020-02-06 US disclosed
EP-3604503-A1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM Ajinomoto Co., Inc. (JP) 2020-02-05 EP disclosed
US-20170370954-A1 Biomarkers for Fatty Liver Disease and Methods Using the Same METABOLON, INC. 2017-12-28 US disclosed
US-20140343865-A1 Biomarkers for Kidney Cancer and Methods Using the Same METABOLON, INC. 2014-11-20 US disclosed
EP-2788763-A2 BIOMARKERS FOR KIDNEY CANCER AND METHODS USING THE SAME Metabolon, Inc. (US) 2014-10-15 EP disclosed
US-20140296134-A1 METHODS AND USES FOR METABOLIC PROFILING FOR CLOSTRIDIUM DIFFICILE INFECTION THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-10-02 US disclosed
EP-2776829-A1 METHODS AND USES FOR METABOLIC PROFILING FOR CLOSTRIDIUM DIFFICILE INFECTION The Board of Regents of The University of Texas System (US) 2014-09-17 EP disclosed
CN-102477068-B Amino acid derivative for preparing thrombus dissolving medicament, and preparation method and application thereof UNIV CAPITAL MEDICAL SCIENCES 2013-07-24 CN disclosed
WO-2013086365-A2 BIOMARKERS FOR KIDNEY CANCER AND METHODS USING THE SAME METABOLON, INC. (US) 2013-06-13 WO disclosed
WO-2013070962-A1 METHODS AND USES FOR METABOLIC PROFILING FOR CLOSTRIDIUM DIFFICILE INFECTION THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2013-05-16 WO disclosed
CN-102477068-A Amino acid derivative for preparing thrombus dissolving medicament, and preparation method and application thereof UNIV CAPITAL MEDICAL 2012-05-30 CN disclosed
EP-0632143-B1 Method for the deposition of large molecules without loss of their properties ENEA ENTE NUOVE TEC (IT) 1997-10-08 EP disclosed
EP-0632143-A1 Method for the deposition of large molecules without less of their properties ENEA ENTE PER LE NUOVE TECNOLOGIE, L'ENERGIA E L'AMBIENTE (IT) 1995-01-04 EP disclosed
EP-0632143-A1 Method for the deposition of large molecules without less of their properties ENEA ENTE PER LE NUOVE TECNOLOGIE, L'ENERGIA E L'AMBIENTE (IT) 1995-01-04 EP disclosed
CN-1031025-A NUTRITIVE EMULSION PREPARATION OTSUKA PHARMA CO LTD (JP) 1989-02-15 CN disclosed