Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8776634 | 0.99 | HSD17B10 (0.40) | HSD17B10HPGDPARP1EPHX1PREP | |
| SCHEMBL30722449 | 0.90 | PARP1 (0.39) | HSD17B10HPGDPARP1EPHX1SMN1; SMN2 | |
| SCHEMBL31411007 | 0.83 | USP2 (0.50) | HSD17B10HPGDEPHX1PREPSMN1; SMN2 | |
| SCHEMBL31473115 | 0.82 | HPGD (0.46) | HSD17B10HPGDEPHX1PREPSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8805314 | 0.80 | PARP1 (0.44) | HSD17B10HPGDPARP1EPHX1SMN1; SMN2 | |
| SCHEMBL3153297 | 0.79 | CHRM5 (0.39) | — | |
| SCHEMBL13994307 | 0.78 | HSD17B10 (0.64) | HSD17B10HPGDPREPSMN1; SMN2NPC1 | |
| SCHEMBL8485936 | 0.78 | HSD17B10 (0.38) | HSD17B10HPGDEPHX1PREPSMN1; SMN2 | |
| SCHEMBL30032926 | 0.77 | NR1H2 (0.43) | HSD17B10HPGDEPHX1PREPNPC1 | |
| SCHEMBL30165850 | 0.77 | HSD17B10 (0.39) | HSD17B10HPGDEPHX1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799202-A1 | PIPERAZINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME, THEIR USE AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996020173-A1 | PIPERAZINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME, THEIR USE AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1996-07-04 | — | — | WO | disclosed |