SCHEMBL8776812

SCHEMBL8776812

C[Si](C)(C)O[Si](C)(C)O[Si](C)(CCCCCCCCCCCOCC(O)CO)O[Si](C)(C)O[Si](C)(C)CCCCCCCCCCCOCC(O)CO

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.48
HTT P42858 1/20 0.34
PLA2G2C Q5R387 1/20 0.32
LPAR5 Q9H1C0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13295797 0.93 USP2 (0.51) USP2HTTPLA2G2CLPAR5
SCHEMBL20023896 0.89 USP2 (0.47) USP2HTTPLA2G2C
SCHEMBL20437550 0.89 USP2 (0.47) USP2HTTPLA2G2C
SCHEMBL27273283 0.88 USP2 (0.40) USP2
SCHEMBL27273297 0.88 USP2 (0.48) USP2HTTPLA2G2CLPAR5
SCHEMBL11925337 0.88 USP2 (0.46) USP2HTT
SCHEMBL20437548 0.88 USP2 (0.46) USP2HTT
SCHEMBL20437549 0.87 USP2 (0.57) USP2HTTPLA2G2CLPAR5
SCHEMBL20437566 0.87 USP2 (0.57) USP2HTTPLA2G2CLPAR5
SCHEMBL27273282 0.87 USP2 (0.50) USP2HTTPLA2G2CLPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0475130-B1 Siloxane derivative, its use as emulsifier and cosmetic preparations KAO CORP (JP) 1997-12-03 EP disclosed
US-5466849-A Cosmetics KAO CORPORATION (JP) 1995-11-14 US disclosed
US-5306838-A Cosmetics, storage stability KAO CORPORATION (JP) 1994-04-26 US disclosed
US-5144054-A Reaction Products with Alkenyl Glyceryl Ether KAO CORPORATION (JP) 1992-09-01 US disclosed
EP-0475130-A2 Siloxane derivatives, producing method thereof and agents including siloxane derivative KAO CORPORATION (JP) 1992-03-18 EP disclosed