Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467327 | 0.88 | MAPT (0.43) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL18317710 | 0.82 | MAPT (0.42) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL18317395 | 0.81 | MAPT (0.45) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL18317679 | 0.81 | MAPT (0.40) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL27865333 | 0.76 | TNF (0.37) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL18321128 | 0.75 | MAPT (0.43) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL27826181 | 0.73 | KDM4E (0.37) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL31303921 | 0.73 | TNF (0.62) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL6007118 | 0.72 | KDM4E (0.38) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL3820783 | 0.72 | MAPT (0.43) | KDM4EMAPTNPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762100-A | Selective sphingosine-1-phosphate receptor modulators and chiral synthesis methods | RECEPTOS INC | 2012-10-31 | — | — | CN | disclosed |
| CN-102753022-A | Selective heterocyclic sphingosine 1-phosphate receptor modulators | RECEPTOS INC | 2012-10-24 | — | — | CN | disclosed |
| CN-102724880-A | Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis | RECEPTOS INC | 2012-10-10 | — | — | CN | disclosed |
| EP-0811629-A1 | OPTICALLY ACTIVE BIDENTATE PHOSPHINE LIGAND/PALLADIUM COMPLEX | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-12-10 | — | — | EP | disclosed |