Benzophenone

Benzophenone

SCHEMBL8777480

O=C(O)c1cc(-c2ccccc2)c(C(=O)O)c(C(=O)O)c1C(=O)O.O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 4/20 0.52
ATM Q13315 2/20 0.50
CDC25B P30305 2/20 0.50
ALDH1A1 P00352 2/20 0.47
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SRD5A2 P31213 1/20 0.46
CYP2C8 P10632 1/20 0.45
CYP2C9 P11712 1/20 0.45
KDM4E B2RXH2 1/20 0.45
PTPN1 P18031 1/20 0.44
POLB P06746 2/20 0.43
CDC25A P30304 1/20 0.42
HSD17B10 Q99714 1/20 0.42
HNF4A P41235 1/20 0.42
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41
SERPINE1 P05121 1/20 0.41
NR4A1 P22736 1/20 0.41
KMO O15229 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49835 0.91 PTPN1 (0.50) AKR1C3ATMCDC25BALDH1A1PTPN1
SCHEMBL29478249 0.91 PTPN1 (0.50) AKR1C3ATMCDC25BALDH1A1PTPN1
Benzene SCHEMBL3625753 0.91 PTPN1 (0.50) AKR1C3ATMCDC25BALDH1A1PTPN1
SCHEMBL28702995 0.90 PTPN1 (0.49) AKR1C3ATMCDC25BALDH1A1PTPN1
Methane SCHEMBL29177518 0.90 PTPN1 (0.49) AKR1C3ATMCDC25BALDH1A1PTPN1
Hydrochloric Acid SCHEMBL15549923 0.90 PTPN1 (0.49) AKR1C3ATMCDC25BALDH1A1PTPN1
SCHEMBL8804751 0.90 PTPN1 (0.49) AKR1C3ATMCDC25BALDH1A1PTPN1
SCHEMBL29404854 0.90 PTPN1 (0.49) AKR1C3ATMCDC25BALDH1A1PTPN1
Water SCHEMBL7131147 0.90 PTPN1 (0.49) AKR1C3ATMCDC25BALDH1A1PTPN1
SCHEMBL28354634 0.90 PTPN1 (0.49) AKR1C3ATMCDC25BALDH1A1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0419804-B1 Multilayer structures of different electroactive materials and methods of fabrication thereof IBM (US) 1997-12-29 EP disclosed
US-5021129-A Multilayer structures of different electroactive materials and methods of fabrication thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1991-06-04 US disclosed
EP-0419804-A2 Multilayer structures of different electroactive materials and methods of fabrication thereof International Business Machines Corporation (US) 1991-04-03 EP disclosed