Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 14/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.33 |
| ▸ | PDE4A | P27815 | 6/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3029536 | 1.00 | HDAC1 (0.39) | HDAC1HDAC2PDE4BWDR5ROCK1 | |
| SCHEMBL3029537 | 1.00 | HDAC1 (0.39) | HDAC1HDAC2PDE4BWDR5ROCK1 | |
| SCHEMBL870919 | 0.90 | PDE4B (0.44) | HDAC1HDAC2PDE4BCNR2 | |
| SCHEMBL870918 | 0.90 | PDE4B (0.44) | HDAC1HDAC2PDE4BCNR2 | |
| SCHEMBL872679 | 0.89 | PDE4B (0.38) | HDAC1HDAC2PDE4BWDR5CNR2 | |
| SCHEMBL870877 | 0.89 | PDE4B (0.38) | HDAC1HDAC2PDE4BWDR5KCNH2 | |
| SCHEMBL871169 | 0.88 | PDE4B (0.37) | HDAC1HDAC2PDE4BWDR5CNR2 | |
| SCHEMBL3024938 | 0.88 | PDE4B (0.37) | HDAC1HDAC2PDE4BWDR5CNR2 | |
| SCHEMBL3032903 | 0.88 | HDAC1 (0.40) | HDAC1HDAC2PDE4BWDR5ROCK1 | |
| SCHEMBL871170 | 0.88 | PDE4B (0.47) | HDAC1HDAC2PDE4BROCK1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077801-A1 | Chemical Compounds 637 | ALCON RESEARCH, LTD. | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077801-A1 | Chemical Compounds 637 | PDE4A, PDE4B, PDE3B | HDAC1 596/4885HDAC2 899/4885PDE4B 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.