Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | PTGES | O14684 | 3/20 | 0.47 |
| ▸ | TOP1 | P11387 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778045 | 0.90 | TSHR (0.49) | TRPV1ALDH1A1NPSR1MAOBPTGES | |
| SCHEMBL8778002 | 0.89 | F10 (0.47) | ALDH1A1NPSR1MAOBPTGESMEN1 | |
| SCHEMBL8777846 | 0.82 | GAA (0.58) | ALDH1A1NPSR1MEN1GAAKMT2A | |
| SCHEMBL8803611 | 0.82 | TRPV1 (0.47) | TRPV1ALDH1A1NPSR1MAOBPTGES | |
| SCHEMBL8777976 | 0.81 | TSHR (0.59) | ALDH1A1MEN1GAAKMT2ARECQL | |
| Hydrochloric Acid SCHEMBL8777867 | 0.81 | TSHR (0.58) | ALDH1A1MEN1GAAKMT2ARECQL | |
| SCHEMBL8805518 | 0.80 | TRPV1 (0.46) | TRPV1ALDH1A1NPSR1MAOBPTGES | |
| SCHEMBL8805516 | 0.80 | TRPV1 (0.46) | TRPV1ALDH1A1NPSR1MAOBPTGES | |
| SCHEMBL3661171 | 0.77 | TOP1 (0.57) | ALDH1A1TOP1TOP2ATOP2BMEN1 | |
| SCHEMBL9417251 | 0.76 | MEN1 (0.60) | ALDH1A1MEN1GAAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665216-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5576335-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0665216-A1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |