SCHEMBL8778452

SCHEMBL8778452

COC1CCCNC(=O)C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.38
FKBP5 Q13451 1/20 0.37
CRBN Q96SW2 1/20 0.37
PDE4B Q07343 5/20 0.35
PDE4A P27815 4/20 0.35
PDE4C Q08493 4/20 0.35
PDE4D Q08499 4/20 0.35
CYP3A4 P08684 2/20 0.35
VEGFA P15692 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
ALOX15 P16050 1/20 0.35
CREBBP Q92793 1/20 0.35
KDM4E B2RXH2 1/20 0.35
PDE5A O76074 1/20 0.35
TNF P01375 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18995286 0.88
SCHEMBL15893898 0.88
SCHEMBL19338318 0.88
SCHEMBL9070667 0.74
SCHEMBL3734132 0.74
SCHEMBL5759844 0.74
SCHEMBL7620666 0.72
SCHEMBL2483160 0.72
SCHEMBL2731065 0.71 BRD4 (0.41) OR51E2KMT2AL3MBTL1
SCHEMBL8299348 0.69 CRBN (0.40) OR51E2FKBP5CRBNALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0804530-A1 BLEACHING COMPOSITIONS AND ADDITIVES COMPRISING BLEACH ACTIVATORS HAVING ALPHA-MODIFIED LACTAM LEAVING-GROUPS THE PROCTER & GAMBLE COMPANY (US) 1997-11-05 EP disclosed
US-5635103-A Bleaching compositions and additives comprising bleach activators having alpha-modified lactam leaving-groups THE PROCTER & GAMBLE COMPANY (US) 1997-06-03 US disclosed
WO-1996022350-A1 BLEACHING COMPOSITIONS AND ADDITIVES COMPRISING BLEACH ACTIVATORS HAVING ALPHA-MODIFIED LACTAM LEAVING-GROUPS THE PROCTER & GAMBLE COMPANY (US) 1996-07-25 WO disclosed
US-4663319-A LIVER DISORDERS TANABE SEIYSKU CO., LTD. (JP) 1987-05-05 US disclosed
US-3931292-A Preparation of omega-amino-substituted beta-alkoxycarboxylic esters STAMICARBON B.V. (NL) 1976-01-06 US disclosed